Gut Hormone FGF15 Changes How Mice Respond to Weight Loss

May 4, 2026
Read time: <5 mins

A new study from the University of Michigan’s Caswell Diabetes Institute found that different weight loss methods can affect the body in very different ways beyond overall weight loss. Researchers identified a gut hormone called FGF15 as an important factor in preserving lean mass during rapid weight loss, with diet changes and semaglutide showing notably different effects. Read the full article to learn why the method of weight loss may matter as much as the pounds lost.

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