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Drug Combination Reduces Breast Cancer Risk and Improves Metabolic Health in Rats

April 25, 2025

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Read time:

<5 mins
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Presented by Health Lab

A University of Michigan study, led by kinesiology professor Erin Giles of the Rogel Cancer Center, found that a combination of bazedoxifene and conjugated estrogens (BZA/CE) reduced breast cancer risk and improved metabolic health in obese rats—offering a promising alternative to tamoxifen. Unlike tamoxifen, which can raise diabetes risk and trigger hot flashes, BZA/CE lowered body fat and enhanced insulin sensitivity. Read on to learn how continued research could benefit women facing breast cancer and those navigating menopause.

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