How Holding Your Pee Can Rewire Your Brain

June 23, 2025

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Read time:

<5 mins
V2restroom Sign Holding Urine Bathroom
Presented by Health Lab

A Michigan Medicine specialist warns that holding your pee too long can actually rewire how your brain and bladder communicate. Dr. Giulia Ippolito, a neuro-urologist and pelvic reconstruction expert, explains how chronic “holding” can affect your bladder and potentially lead to kidney issues. For professions or lifestyles where bathroom breaks are tough to come by, this could quietly be creating long-term problems. Find out what happens when your body’s natural signals get ignored, and how to retrain your bladder before potentially serious implications occur.

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