The University of Michigan is leading the way in transportation and robotics research with innovations in self-driving cars, prosthetics, and human-technology collaboration. During a recent visit, the President’s Council of Advisors on Science and Technology (PCAST) explored groundbreaking projects at Mcity, UMTRI, and other top facilities, highlighting advancements that could reshape safety, mobility, and human capabilities. The article examines these innovations and PCAST’s role in guiding their development, offering a glimpse into the future of technology.