Researchers Use a New Approach to Hit an ‘Undruggable’ Target

February 15, 2023


Read time:

5-15 mins
Cancer Protein STAT5 Cell Yellow
Presented by Health Lab

STAT5, a key player in the development and progression of some blood cancers, has long been an appealing target against cancer, but after decades of research, it has been moved to the “undruggable” category, which indicates that a protein is currently pharmacologically incapable of being targeted. Researchers from the University of Michigan found that while they may be unable to target STAT5 pharmacologically, they discovered that eliminating the protein from the cell structure is possible and can change specific cancer treatments forever.

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