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High Levels of Ammonia in Colon Tumors inhibits T cell growth and response to immunotherapy

December 23, 2022


Read time:

5-15 mins
Mouse Model Human Colorectal Cancer
Presented by Health Lab

Can high levels of ammonia in tumors have a direct effect on cancer? Researchers found that there is a direct correlation between tumor production and ammonia present; due to ammonia lowering T cell production, it creates an environment for tumors to thrive. Hannah Bell, Ph.D., a postdoctoral fellow in cancer biology, discusses the usefulness of possible treatments involving FDA-approved drugs for hyperammonemia and its effect on tumor production.

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